Hands, whether gloved or ungloved, are one of the main methods for spreading infection or for transferring microbial contamination. The use of เจลล้างมือแอลกอฮอล์ is part of the process of good contamination control for personnel working in hospital environments, or those associated with aseptic processing and within cleanrooms. Although there are many different types of hand sanitizers available there are differences with their usefulness and many do not meet the European standard for hand sanitization.
Personnel working in hospitals and cleanrooms carry various types of bacteria on the hands and the like microorganisms can be easily transferred for every person or from person to equipment or critical surfaces. Such bacteria are either present on the skin not multiplying (transient flora, which can include a range of ecological bacteria like Staphylococcus and Pseudomonas) or are multiplying bacteria released through the skin area (household flora such as the genera of Staphylococcus, Micrococcus and Propionibacterium). Of the two groups, residential flora are more difficult to remove. For critical operations, some safety is provided by wearing gloves. However safety gloves are not ideal for all activities and gloves, or even frequently cleaned or when they are of an unsuitable style, will pick up and move contamination.
Consequently, the sanitization of fingers (either gloved or ungloved) is an essential part of contamination control either in hospitals, to prevent staff-to-patient cross contamination or before venture clinical or surgical operations; and for aseptic preparations like the dispensing of medications. Furthermore, not just is using a hand sanitizer required just before venture such programs, additionally it is crucial that the sanitizer is effective at getting rid of a high population of microorganisms. Studies show that if a minimal number of microorganisms continue right after the use of a sanitizer then the subpopulation can develop that is immune to long term programs.
There are numerous commercially available hand sanitisers with all the most commonly used types being alcohol-based liquids or gels. As with other types of disinfectants, hand sanitizers work well against different เจลล้างมือแอลกอฮอล์ 70 depending upon their mode of activity. With the most frequent alcohol based hand sanitizers, the mode of action leads to bacterial cell death through cytoplasm leakage, denaturation of protein and eventual cell lysis (alcohols are one of the so-called ‘membrane disrupters’). The advantages of employing alcohols as hand sanitizers incorporate a relatively affordable, little odour and a quick evaporation (limited residual activity results in shorter contact times). Furthermore alcohols have a proven cleansing action.
When deciding on a hand sanitiser the pharmaceutical organisation or hospital will need to consider if the application will be created to human skin or to gloved hands, or both, and should it be necessary to be sporicidal. Hand sanitisers fall into two groups: alcohol based, which are more widespread, and non-alcohol based. Such considerations impact both upon cost and the safety and health in the staff using the hand sanitiser since many commonly available alcohol based sanitisers can cause excessive drying of your skin; and a few non-alcohol based sanitisers can be irritating towards the skin. Alcohol hand sanitizers are created to avoid irritation through possessing hypoallergenic properties (colour and fragrance free) and ingredients which afford skin protection and care through re-fatting agents.
Alcohols have a long background of use as เจลล้างมือแอลกอฮอล์ due to inherent antiseptic properties against bacteria and some viruses. To work some water is needed to be combined with alcohol to exert effect against microorganisms, with the very best range falling between 60 and 95% (most commercial hand sanitizers are around 70%). By far the most widely used alcohol based apkdug sanitisers are Isopropyl alcohol or some form of denatured ethanol (including Industrial Methylated Spirits). The greater common non-alcohol based sanitisers contain either chlorhexidine or hexachlorophene. Additives can additionally be contained in hand sanitizers in order to boost the antimicrobial properties.
Before entering a hospital ward or clean area hands ought to be washed using soap and water for approximately twenty seconds. Handwashing removes around 99% of transient microorgansisms (though it does not kill them) (4). From that point on, whether gloves are worn or otherwise, regular hygienic hand disinfection should happen to remove any subsequent transient flora as well as reduce the potential risk of the contamination as a result of resident skin flora.